TABLE 4.
Binding Parameters from MA1
|
VT (mL/cm3) (%COV) |
VT/fP (mL/cm3) (%COV) |
BPND (%COV) |
BPP (mL/cm3) (%COV) |
BPF (mL/cm3) (%COV) |
||||||
| Region | Test | Retest | Test | Retest | Test | Retest | Test | Retest | Test | Retest |
| Putamen | 1.27 (11%) | 1.31 (6%) | 10.07 (6%) | 10.14 (27%) | 0.79 (20%) | 0.80 (25%) | 0.52 (12%) | 0.54 (19%) | 3.96 (14%) | 4.11 (39%) |
| Nucleus accumbens | 1.21 (15%) | 1.22 (7%) | 9.69 (6%) | 9.49 (22%) | 0.70 (16%) | 0.67 (14%) | 0.46 (18%) | 0.45 (8%) | 3.57 (16%) | 3.46 (24%) |
| Caudate | 1.03 (13%) | 1.06 (6%) | 8.32 (6%) | 8.38 (26%) | 0.45 (18%) | 0.45 (30%) | 0.28 (15%) | 0.29 (23%) | 2.20 (23%) | 2.35 (46%) |
| Occipital cortex | 1.02 (16%) | 1.05 (8%) | 8.29 (3%) | 8.19 (22%) | 0.44 (12%) | 0.44 (12%) | 0.27 (19%) | 0.28 (6%) | 2.18 (13%) | 2.16 (24%) |
| Centrum semiovale | 0.97 (18%) | 1.02 (10%) | 7.84 (6%) | 7.79 (18%) | 0.36 (21%) | 0.39 (22%) | 0.22 (30%) | 0.25 (22%) | 1.72 (26%) | 1.76 (12%) |
| Temporal cortex | 0.95 (15%) | 0.99 (8%) | 7.64 (3%) | 7.64 (23%) | 0.34 (22%) | 0.36 (21%) | 0.20 (23%) | 0.22 (17%) | 1.53 (21%) | 1.61 (29%) |
| Frontal cortex | 0.95 (14%) | 0.98 (8%) | 7.59 (4%) | 7.59 (25%) | 0.34 (22%) | 0.35 (27%) | 0.20 (19%) | 0.21 (25%) | 1.47 (19%) | 1.56 (39%) |
| Parietal cortex | 0.93 (14%) | 0.95 (9%) | 7.50 (4%) | 7.35 (24%) | 0.32 (27%) | 0.30 (22%) | 0.18 (28%) | 0.18 (21%) | 1.38 (32%) | 1.32 (35%) |
| Cerebellum | 0.71 (17%) | 0.73 (12%) | 5.80 (3%) | 5.74 (22%) | ||||||
%COV = coefficient of variation (intersubject variability).
Values are mean of n = 5 subjects (n = 4 for VT/fP and BPF), with each value measured twice in test and retest scans.