TABLE 5.

Test–Retest Reproducibility of Volume of Distribution and Binding Potential

	MA1 (t* = 40 min)									SRTM
	VT (n = 5)			BPND (n = 5)			BPP (n = 5)			BPND (n = 5)
Region	*aTRV	*TRV	†ICC	*aTRV	*TRV	†ICC	*aTRV	*TRV	†ICC	*aTRV	*TRV	†ICC
Putamen	9%	−4% ± 11%	0.23 [–0.64, 0.87]	16%	0% ± 23%	0.58 [–0.33, 0.94]	15%	−4% ± 24%	−0.01 [–0.76, 0.80]	14%	−1% ± 22%	0.64 [–0.24, 0.95]
Nucleus accumbens	7%	−2% ± 10%	0.66 [–0.20, 0.96]	17%	4% ± 22%	0.15 [–0.69, 0.85]	14%	0% ± 23%	−0.17 [–0.83, 0.74]	14%	2% ± 18%	0.17 [–0.68, 0.86]
Caudate	7%	−3% ± 8%	0.68 [–0.17, 0.96]	18%	2% ± 21%	0.73 [–0.08, 0.97]	14%	−3% ± 19%	0.55 [–0.36, 0.94]	15%	2% ± 20%	0.83 [0.19, 0.98]
Occipital cortex	8%	−4% ± 8%	0.77 [0.03, 0.97]	12%	0% ± 16%	0.27 [–0.62, 0.88]	13%	−5% ± 18%	0.15 [–0.69, 0.85]	15%	3% ± 17%	0.36 [–0.55, 0.91]
Centrum semiovale	10%	−6% ± 11%	0.71 [–0.12, 0.96]	18%	−9% ± 19%	0.63 [–0.26, 0.95]	24%	−15% ± 22%	0.53 [–0.38, 0.94]	11%	−4% ± 14%	0.71 [–0.11, 0.96]
Temporal cortex	8%	−4% ± 9%	0.71 [–0.12, 0.96]	14%	−4% ± 24%	0.57 [–0.34, 0.94]	22%	−10% ± 28%	0.15 [–0.69, 0.85]	18%	−3% ± 26%	0.51 [–0.41, 0.93]
Frontal cortex	7%	−4% ± 7%	0.75 [–0.03, 0.97]	12%	−2% ± 16%	0.85 [0.26, 0.98]	13%	−7% ± 17%	0.69 [–0.14, 0.96]	15%	5% ± 17%	0.85 [0.26, 0.98]
Parietal cortex	5%	−2% ± 7%	0.84 [0.20, 0.98]	21%	6% ± 25%	0.65 [–0.23, 0.96]	22%	2% ± 30%	0.51 [–0.41, 0.93]	21%	9% ± 24%	0.69 [–0.16, 0.96]
Cerebellum	5%	−3% ± 6%	0.90 [0.45, 0.99]

^*TRV = (test value – retest value)/(test value + retest value) × 2, and aTRV is absolute value of TRV.

^†ICC = (BSMSS – WSMSS)/(BSMSS + WSMSS) where BSMSS is mean sum of squares between subjects and WSMSS is mean sum of squares within subjects. ICC is presented with lower and upper bounds of 95% confidence interval in brackets.