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Relationship between arterial 18F-FDG uptake (by PET/CT) and histologic macrophage accumulation. Rabbits that had received GM-CSF (4 atherosclerotic and 2 control) were imaged using 18F-FDG PET/CT. Arterial 18F-FDG uptake was recorded as TBR. Subsequently, the animals were sacrificed and macrophage concentration within aortic wall was determined histologically (%RAM11 staining). There was significant relationship between macrophage staining and TBR (R = 0.76, P = 0.002).
