Table 2.
Univariate and multivariate associations between poor hygiene exposures and immune response phenotype membership
| Exposures | Spontaneous outcome (High) | SEB-stimulated outcome (Th2 modified) | ||||||
|---|---|---|---|---|---|---|---|---|
| Crude | Adjusted | Crude | Adjusted | |||||
| OR | (95 % CI) | OR | (95 % CI) | OR | 95 % CI | OR | 95 % CI | |
| Father agricultural activities (Yes vs. No) |
0.81 | (0.44;1.49) | 0.79 | (0.41;1.51) | 0.57 | (0.33;0.97) | 0.55 | (0.32;0.96) |
| Birth order (≥4th vs. ≤3rd) | 0.44 | (0.22;0.86) | 0.48 | (0.24;0.95) | 2.07 | (1.21;3.56) | 2.04 | (1.18;3.52) |
| Any geohelminth infection (Yes vs. No) |
0.24 | (0.12;0.47) | 0.25 | (0.12;0.50) | 1.68 | (1.00; 2.82) | 1.68 | (0.98; 2.89) |
| Number peri-domiciliary animals (> = 4 vs. <4) |
0.53 | (0.19;1.44) | 0.88 | (0.43;1.82) | 0.92 | (0.54;1.56) | 0.89 | (0.51;1.56) |
ORs adjusted for age, sex, area of residence, ethnicity, and other variables in model