Table 2.
Methodology and quality of inclined studies
| Authors | Year | Research design | Country | Asians/Caucasians | Test method | Measurement units | QUADAS |
|---|---|---|---|---|---|---|---|
| Benson MD [12] | 1986 | Prospective | Indiana | 0/100 | Competitive binding radioimmunoassay | u/ml | 12 |
| Howard BA [13] | 2003 | Retrospective | USA | 0/19 | ELISA | ng/mL | 7 |
| Khan N [14] | 2004 | NA | North Carolina | 0/50 | MALDI-TOF; ELISA | ng/mL | 10 |
| Dai S [16] | 2007 | Retrospective | China | 175/0 | SELDI-TOF-MS; ELISA | Peak intensities | 9 |
| Liu DH [17] | 2007 | NA | China | 275/0 | Protein Chip Array | Peak intensities | 10 |
| Cho WC [15] | 2010 | Retrospective | Hong Kong | 189/0 | SELDI-TOF; quantitative analysis | Peak intensities; ug/mL−1 | 11 |
| Sung HJ [4] | 2011 | Retrospective | South Korea | 380/0 | LC-ESI-MS/MS Analysis; ELISA | ug/mL | 12 |
| Dowling P [18] | 2011 | Retrospective | Ireland | 0/109 | ELISA | ug/mL | 10 |
| Kanoh Y [9] | 2013 | NA | Japan | 37/0 | Latex nephelometry | ug/mL | 7 |
QUADAS quality assessment for studies of diagnostic accuracy (maximum score 14); ELISA enzyme-linked immunosorbent assays; MALDI-TOF matrix assisted laser desorption ionization time of flight; SELDI-TOF-MS surface-enhanced laser desorption/inionation-time of flight-mass spectra; LC-ESI-MS/MS liquid chromatography-electrospray ionisation-tandem mass spectrometry NA unavailable