Table 4.
Genome | |||
---|---|---|---|
P. falciparum 3D7 | P. reichenowi CDC | P. berghei ANKA | |
All PQS | |||
Within a gene | 34 | 40 | 11 |
Upstream (within 2 kb) | 37 | 5 | 30 |
Downstream (within 2 kb) | 7 | 8 | 7 |
No gene within 2 kb | 2 | 0 | 0 |
Total | 80 | 53 | 48 |
Var-associated PQS | |||
Within a var gene | 19 | 33 (inc. 1 pseudogene) | |
Upstream (within 2 kb) | 16 | 0 | |
Downstream (within 2 kb) | 0 | 0 | |
Total var sequences | 103a | 103a | |
Var genes | 63a | 64a | |
Fragments/pseudogenes | 6/34a | 37/22a | |
Pir-associated PQS | |||
Within a pir gene | 3 | 0 | 0 |
Upstream (within 2 kb) | 0 | 1 | 28 |
Downstream (within 2 kb) | 0 | 1 | 6 |
Total pir sequences | 226a | 528a | 299 |
Pir genes | 189a | 351a | 217 |
Fragments/pseudogenes | 0/37a | 118/59a | 0/82 |
Table shows numbers of PQS found in each Plasmodium genome analysed. ‘Fragments/pseudogenes’ refers to the numbers of incomplete, but recognizable, var gene sequences, which are designated as gene fragments or pseudogenes
aIndicates gene numbers taken from Otto et al. [31]