Table 2.
Diagnostic performance* of the Leucocyte Esterase Test (LET) after a reading time of 2 min (“LET 2 m”) and 5 min (“LET 5 m”) in the detection of urogenital Chlamydia Trachomatis (Ct) among male patients, Dermatological Service in Paramaribo, Suriname, 2008–2010
| N | LET + NAAT+ | LET-NAAT+ | LET + NAAT- | LET- NAAT- | Sens. (95 % CI) | Spec. (95 % CI) | PPV (95 % CI) | NPV (95 % CI) | Agr. | Kappa | |
|---|---|---|---|---|---|---|---|---|---|---|---|
| LET 2 m | |||||||||||
| ALL | 412 | 87 | 7 | 197 | 121 | 92.6 % (85.3–97.0) | 38.1 % (32.7–43.6) | 30.6 % (27.3–36.4) | 94.5 % (89.1–97.8) | 50.5 % | 0.179 |
| Sympto-matic patients | 279 | 71 | 6 | 141 | 61 | 92.2 % (83.8–97.1) | 30.2 % (24.0–37.0) | 33.5 % (27.2–40.3) | 91.0 % (81.5–96.6) | 47.3 % | 0.145 |
| Asympto-matic patients | 133 | 16 | 1 | 56 | 60 | 94.1 % (71.3–99.9) | 51.7 % (42.3–61.1) | 22.2 % (13.8–32.9) | 98.4 % (91.2–100) | 57.1 % | 0.193 |
| <25 years | 109 | 29 | 0 | 47 | 33 | 100 % (88.1–100) | 41.3 % (30.4–52.8) | 38.2 % (27.2–50.0) | 100 % (89.4–100) | 56.9 % | 0.272 |
| LET 5 m | |||||||||||
| ALL | 412 | 91 | 3 | 265 | 53 | 96.8 % (91.0–99.3) | 16.7 % (12.7–21.2) | 25.6 % (21.1–30.4) | 94.6 % (85.1–98.9) | 35.0 | 0.068 |
*Sensitivity (Sens.), Specificity (Spec.), Positive Predictive Value (PPV), Negative Predictive Value (NPV), Agreement (Agr.) and Kappa