Table 3.
Diagnostic performance* of the Leucocyte Esterase Test (LET) after a reading time of 2 min (“LET 2 m”) and 5 min (“LET 5 m”) in the detection of urogenital Chlamydia Trachomatis (Ct) among male patients, STI outpatient clinic, Amsterdam, The Netherlands, 2009–2010
| N | LET+ NAAT+ | LET- NAAT+ | LET+ NAAT- | LET- NAAT- | Sens. (95 % CI) | Spec. (95 % CI) | PPV (95 % CI) | NPV (95 % CI) | Agr. | Kappa | |
|---|---|---|---|---|---|---|---|---|---|---|---|
| LET 2 m | |||||||||||
| ALL | 645 | 68 | 20 | 233 | 324 | 77.3 % (67.1–85.5) | 58.1 % (53.9–62.3) | 22.6 % (18.0–27.7) | 94.2 % (91.1–96.4) | 60.8 % | 0.176 |
| Sympto-matic patients | 257 | 44 | 9 | 100 | 104 | 83.0 % (70.2–91.9) | 51.0 % (43.9–58.0) | 30.6 % (23.2–38.8) | 92.0 % (85.4–96.3) | 57.6 % | 0.208 |
| Asympto-matic patients | 379 | 23 | 11 | 129 | 216 | 67.6 % (49.5–82.6) | 62.6 % (57.2–67.7) | 15.1 % (9.8–21.8) | 95.1 % (91.4–97.5) | 63.1 % | 0.026 |
| <25 years | 110 | 18 | 3 | 41 | 48 | 85.7 % (63.7–97.0) | 53.9 % (43.0–64.6) | 30.5 % (19.2–43.9) | 94.1 % (84.8–98.8) | 60.0 % | 0.068 |
| LET 5 m | |||||||||||
| ALL | 645 | 80 | 8 | 330 | 227 | 90.9 % (82.9–96.0) | 40.8 % (36.7–45.0) | 19.6 % (15.9–23.8) | 96.6 % (93.4–98.5) | 47.6 % | 0.125 |
*Sensitivity (Sens.), Specificity (Spec.), Positive Predictive Value (PPV), Negative Predictive Value (NPV), Agreement (Agr.) and Kappa