Table 4.
Studies documenting both community engagement and population coverage (n = 11, in chronological order)
| Author, year and country | Epidemiology (baseline parasitemia) | Population coverage/% | Type of study and the context | Anti-malarial(s) | Additional interventions |
|---|---|---|---|---|---|
| Archibald 1960, Nigeria [45] | 48.7% | 89.7 | Non-RCT Inhabitants of villages in Western Sokoto malaria control campaign |
Chloroquine + pyrimethamine | |
| Clyde 1962, Tanzania [46] | 59.8–64% | 95 | Before and after Participants of all ages were recruited |
Amodiaquine + primaquine | IRS with DDT |
| Roberts 1964a, Kenya [40] | 23% | 95 | Non-RCT Participants of all ages were recruited and were from highlands in Kenya from 2 districts |
Pyrimethamine | |
| Garfield 1983, Nicaragua [27] | 0.42–0.83 cases/1000 population/month | 70 | Before and after (nationwide) Medicine was administered to all persons aged >1 year over 3 days given once to the entire population |
Chloroquine + primaquine | |
| Baukapur 1984, India [34] | 0.18/1000 population/month | 76 | Before and after All persons in 2 villages in Valsad District in Gujarat. Migratory population came from malarious areas during study period |
Chloroquine | NR |
| Pribadi 1986, Indonesia [31] | 13.2% | 93.7 | Before and after Mass chemoprophylaxis among all the individuals in Berakit village |
Chloroquine | |
| Doi 1989b, Indonesia [44] | 30% | 100 | Before and after All aged participants were treated |
SP + primaquine | NR |
| Kaneko 2000, Vanuatu [35] | 62% | 88.3 | Before and after MDA was conducted with all individuals in Aneityum islands |
Chloroquine + primaquine + SP | |
| Von Seidlein 2003, Gambia [42] | 41.6% | 85 | RCT/Cluster RCT Individuals older than 6 months and all non-pregnant women in 9 villages and placebo in other 9 villages |
AS + SP | |
| Shekalaghe 2011, Tanzania [12] | 0% by microscope and 2.6% by PCR | 93 | RCT/Cluster RCT Individuals above 1 year were included. People who had received ACTs in 2 weeks prior to the study, pregnant women and people with anaemia received different drug regimen. Four each intervention and control randomly assigned |
AS + SP + primaquine | Vector control, larviciding |
| Lwin 2015, Thai–Myanmar border [25] | 7.3% by microscopy and 18.4% by uPCR in one study village | 40 | Before and after Study population consisted of all the villagers excluding children <14 years and pregnant women in Thai–Myanmar border |
Dihydro-artemesinin + peperaquine | NR |