Table 1.
Hospitalization time | Day 35 | Day 38 | Day 42 | Day 45 | Day 49 | Day 52 | Day 56 | Day 59 | Day 65 | Day 68 | Day 72 |
---|---|---|---|---|---|---|---|---|---|---|---|
WBC (×106 cell/ml) | 25.04 | 17.5 | 17.9 | 18.1 | 14.5 | 18.35 | 11.4 | 10.0 | 10.5 | 6.6 | 8.56 |
Neutrophil (%) | 94.9 | 80.9 | 79.0 | 80.9 | 75.9 | 86.9 | 79.4 | 77.9 | 63.3 | 69.5 | 78.7 |
Procalcitonin (ng/mL) | 2.25 | 0.75 | 6.95 | 0.89 | 0.10 | 0.1 | 0.10 | 0.05 | 0.06 | 0.11 | 0.05 |
CSF leukocyte (cell/μL) | 1800 | 270 | 2540 | 432 | 70 | 1395 | 18 | 47 | 57 | 31 | 4 |
CSF neutrophil (%) | 95 | 71 | 89 | 24 | 20 | 85 | 71 | 78 | 2 | 22 | NA |
CSF lymphocyte (%) | 5 | 29 | NA | 76 | 80 | 15 | 29 | 22 | 98 | 78 | NA |
CSF protein (g/L) | 7 | 1.99 | 2.34 | 2.58 | 0.94 | 1.96 | 1.23 | 0.74 | 2.7 | 0.8 | 0.67 |
CSF glucose (mmol/L) | 0.1 | 0.1 | 0.1 | 2.0 | 1.7 | 1.1 | 1.6 | 2.3 | 1.7 | 3.4 | 3 |
CSF culture | Neg | Neg | Neg | Neg | Neg | Neg | Neg | Neg | Neg | Neg | Neg |
Urea (mmol/L) | 5.0 | 7.1 | 7.0 | 5.5 | 5.4 | NA | 2.9 | 6.3 | 5.6 | 5.3 | 7.0 |
Creatinine (μmol/L) | 87 | 58 | 55 | 51 | 61 | NA | 58 | 40 | 70 | 49 | 60 |
CSF PCR | Not indicated | Not indicated | Not indicated | Ab | Ab | Ab | Ab | Neg | Neg | Neg | Neg |
Antibiotic therapy | Mer 1 g/6 hours + Van 1 g/12 hours | Mer 1 g/6 hours + Col 1 MIU/8 hours | Mer 2 g/8 hours + Col 2 MIU/8 hours |
Ab Acinetobacter baumannii, Col colistin, CSF cerebrospinal spinal fluid, Mer meropenem, MIU million international unit, NA not available, Neg negative, PCR polymerase chain reaction, Van vancomycin, WBC white blood cell