Table 2.
Relationship between dietary interventions (hemin and fat) and outcome variables in A/J Min/+ mice
Hemin+ vs. Hemin− | High fat vs. low fat | ||||
---|---|---|---|---|---|
Coefficient | p-value | Coefficient | p-value | ||
Colon | |||||
Flat ACF | Number per animal | −13.0 [−25.1– −0.9] | 0.036 | 5.0 [−7.2–17.2] | 0.421 |
Average Size | −0.000 [−0.003–0.002] | 0.862 | 0.002 [−0.001–0.004] | 0.142 | |
Load | −0.18 [−0.35– −0.01] | 0.040 | 0.14 [−0.03–0.31] | 0.105 | |
Tumor | Number per animal | −1.0 [−4.0–2.0] | 0.513 | 1.0 [−2.0─4.0] | 0.515 |
Average Size | −0.28 [−0.67–0.13] | 0.181 | 0.66 [0.23–1.07] | 0.002 | |
Load | −0.55 [−3.60–2.50] | 0.723 | 1.39 [−1.69–4.46] | 0.377 | |
Small intestine | |||||
Tumor | Number per animal | 2.0 [−5.2–9.2] | 0.588 | 6.0 [−1.3–13.3] | 0.107 |
Average Size | 0.00 [−0.06–0.58] | 1.000 | 0.12 [0.07–0.18] | <0.001 | |
Load | 1.13 [−2.52–4.78] | 0.544 | 5.54 [1.86–9.21] | 0.031 | |
Fecal Parameters | |||||
TBARS | 7.1 [3.8–10.4] | <0.001 | 5.3 [1.9–8.6] | 0.002 | |
Fecal water content | 4.5 [1.9–7.0] | 0.001 | −2.7 [−5.2– −0.1] | 0.045 |
Regression coefficients [95 % confidence interval] from quantile regression are presented. Significant results (p < 0.05) are shown in bold text