Table 1.
Characteristic | Diabetes (n=3681) | No diabetes (n=7708) | |||||
---|---|---|---|---|---|---|---|
Long DAPT (n=1853) | Short DAPT (n=1828) | P value | Long DAPT (n=3848) | Short DAPT (n=3860) | P value | ||
Mean (SD) age (years) | 63.7 (10.0) | 63.6 (9.9) | 0.60 | 62.8 (11.1) | 62.8 (10.8) | 0.73 | |
Men | 64.0 (1186/1853) | 65.8 (1202/1828) | 0.27 | 72.0 (2770/3848) | 72.2 (2787/3860) | 0.83 | |
Hypertension | 87.4 (1618/1852) | 87.0 (1591/1828) | 0.76 | 75.1 (2889/3846) | 74.5 (2873/3856) | 0.54 | |
Hypercholesterolaemia | 72.3 (1326/1834) | 71.9 (1302/1810) | 0.81 | 60.7 (2308/3803) | 60.1 (2296/3821) | 0.59 | |
Smoking | 17.6 (274/1558) | 19.5 (301/1543) | 0.17 | 23.6 (799/3381) | 24.0 (816/3403) | 0.74 | |
Previous myocardial infarction | 22.6 (371/1638) | 25.2 (416/1652) | 0.09 | 21.2 (742/3505) | 20.2 (706/3501) | 0.30 | |
Previous PCI | 19.5 (321/1646) | 21.4 (354/1658) | 0.19 | 15.7 (550/3511) | 16.6 (585/3516) | 0.27 | |
Previous CABG | 7.7 (126/1645) | 7.3 (121/1657) | 0.70 | 5.6 (196/3507) | 5.4 (190/3518) | 0.73 | |
Previous stroke | 4.4 (54/1230) | 6.2 (78/1257) | 0.05 | 3.3 (81/2457) | 3.1 (78/2482) | 0.76 | |
Creatinine >106.08 μmol/L | 10.9 (79/725) | 8.2 (59/720) | 0.08 | 7.4 (133/1804) | 6.9 (125/1812) | 0.58 | |
Clinical presentation: | |||||||
Stable angina pectoris | 62.5 (1159/1853) | 59.8 (1094/1828) | 0.09 | 56.6 (2178/3847) | 57.7 (2227/3860) | 0.34 | |
Acute coronary syndrome | 37.5 (694/1853) | 40.2 (734/1828) | 43.4 (1669/3847) | 42.3 (1633/3860) | |||
STEMI | 3.3 (61/1853) | 3.0 (55/1828) | — | 6.4 (247/3847) | 6.9 (265/3860) | — | |
NSTEMI | 7.4 (137/1853) | 7.2 (131/1828) | — | 9.0 (348/3847) | 8.5 (328/3860) | — | |
Unstable angina | 26.8 (496/1853) | 30.0 (548/1828) | — | 27.9 (1074/3847) | 26.9 (1040/3860) | — | |
Discharge drugs: | |||||||
Aspirin | 99.9 (1292/1293) | 99.9 (1277/1278) | 0.99 | 99.5 (2693/2706) | 99.8 (2694/2699) | 0.06 | |
Clopidogrel | 99.8 (1290/1293) | 99.6 (1273/1278) | 0.47 | 99.7 (2699/2706) | 99.6 (2688/2699) | 0.49 | |
β blockers | 71.5 (765/1070) | 70.8 (759/1072) | 0.72 | 70.0 (1555/2222) | 68.4 (1527/2232) | 0.26 | |
ACEI/ARB | 60.3 (645/1070) | 62.6 (671/1072) | 0.27 | 56.9 (1265/2222) | 57.1 (1275/2232) | 0.90 | |
Statins | 86.5 (926/1070) | 87.7 (940/1072) | 0.43 | 86.8 (1928/2222) | 88.1 (1966/2232) | 0.19 | |
Mean (SD) diseased vessels/patient | 1.53 (0.9) | 1.54 (0.9) | 0.79 | 1.48 (0.8) | 1.49 (0.8) | 0.81 | |
Mean (SD) No of treated vessels/patient | 1.22 (0.5) | 1.25 (0.5) | 0.15 | 1.21 (0.4) | 1.20 (0.4) | 0.41 | |
Mean (SD) No of stents/patient | 1.58 (0.9) | 1.60 (0.9) | 0.64 | 1.51 (0.8) | 1.48 (0.8) | 0.31 | |
Mean (SD) No of lesions stented/patient | 1.33 (0.6) | 1.34 (0.6) | 0.83 | 1.26 (0.5) | 1.26 (0.5) | 0.53 | |
Mean (SD) total stent length/patient (mm) | 39.0 (26.1) | 39.3 (26.7) | 0.85 | 34.6 (22.9) | 33.9 (23.1) | 0.35 | |
Mean (SD) smallest stent implanted (mm) | 3.0 (0.5) | 3.0 (0.4) | 0.35 | 3.1 (0.8) | 3.1 (0.5) | 0.78 | |
Type of drug eluting stent: | |||||||
PES | 4.1 (75/1844) | 4.2 (76/1820) | <0.001 | 4.8 (182/3831) | 4.8 (183/3840) | <0.001 | |
SES | 4.3 (80/1844) | 3.7 (68/1820) | 11.1 (425/3831) | 2.5 (96/3840) | |||
EES | 39.4 (727/1844) | 34.7 (631/1820) | 35.4 (1357/3831) | 30.9 (1185/3840) | |||
ZES | 47.5 (875/1844) | 52.9 (962/1820) | 44.1 (1689/3831) | 57.0 (2190/3840) | |||
BES | 4.0 (74/1844) | 3.8 (70/1820) | 4.0 (154/3831) | 4.2 (160/3840) | |||
Mixed | 0.5 (9/1844) | 0.4 (8/1820) | 0.5 (19/3831) | 0.3 (13/3840) | |||
Other | 0.2 (4/1844) | 0.3 (5/1820) | 0.1 (5/3831) | 0.3 (13/3840) | |||
Stented coronary artery: | |||||||
Left main | 2.3 (23/998) | 2.7 (27/1002) | 0.58 | 2.3 (54/2369) | 2.2 (52/2372) | 0.84 | |
LAD | 62.5 (726/1161) | 65.5 (763/1165) | 0.14 | 62.8 (1657/2639) | 62.3 (1656/2659) | 0.70 | |
LCx | 35.1 (381/1087) | 33.0 (358/1085) | 0.31 | 31.2 (778/2497) | 30.7 (758/2472) | 0.71 | |
RCA | 39.7 (428/1078) | 39.8 (434/1091) | 0.97 | 34.5 (862/2497) | 30.6 (868/2508) | 0.95 | |
Bifurcation | 18.4 (115/624) | 18.8 (115/612) | 0.87 | 16.0 (225/1410) | 14.3 (203/1424) | 0.21 | |
Chronic total occlusion | 2.0 (22/1084) | 2.7 (29/1083) | 0.32 | 2.3 (51/2240) | 2.4 (55/2247) | 0.71 |
BES=biolimus eluting stent; CABG=coronary artery bypass graft; EES=everolimus eluting stent; GFR=glomerular filtration rate; LAD=left anterior descending artery; NSTEMI=non-ST elevation myocardial infarction; PCI=percutaneous coronary intervention; PES=paclitaxel eluting stent; SES=sirolimus eluting stent; STEMI= ST elevation myocardial infarction; SVG=saphenous vein graft; ZES=zotarolimus eluting stent.