Figure 3.

Levels of collagen/matrix metalloproteinase-1 (MMP-1) ratio (CMR) in relation to hepatitis C virus–nonstructural protein-4 (HCV-NS4) concentration in absence and presence of schistosomiasis and its impact on the progression rates of liver fibrosis. (A) Levels of CMR in patients with significant fibrosis (F2-F4), (B) levels of CMR in patients with cirrhosis (F4), and (C) the risk of elevated CMR on the progression rates of liver fibrosis. Statistically significant differences between groups were determined using the nonparametric Mann–Whitney U test.