Table 1.
Characteristics of patients with HCV monoinfection and HCV/Schistosoma mansoni coinfection
| Variables | Group I (N = 104) | Group II (N = 186) | P value |
|---|---|---|---|
| HCV monoinfection | HCV/S. mansoni coinfection | ||
| Age (years) | 42.7 ± 8.6 | 43.9 ± 7.2 | NS† |
| ALT (U/L)* | 73.3 ± 37.3 | 75.0 ± 43.9 | NS† |
| AST (U/L)* | 55.5 ± 34.2 | 63.0 ± 34.5 | NS† |
| ALP (U/L)* | 88.0 ± 33.8 | 94.0 ± 38.5 | NS‡ |
| PT-INR* | 1.1 ± 0.1 | 1.2 ± 0.07 | NS† |
| Total bilirubin (mg/dL)* | 0.84 ± 0.4 | 0.88 ± 0.5 | NS† |
| Albumin (g/L)* | 43.0 ± 0.3 | 41.0 ± 0.4 | NS† |
| Platelet count (109/L)* | 193.5 ± 50.2 | 175.3 ± 49.8 | NS‡ |
ALP = alkaline phosphatase; ALT = alanine aminotransferase; AST = aspartate aminotransferase; HCV = hepatitis C virus; NS = nonsignificant; PT-INR = prothrombin time–international normalized ratio. Variables were expressed as mean ± standard deviation. P values were corrected for multiple comparisons using Bonferroni correction. Findings with P < 0.05 after correction were considered significant.
Reference values: ALT = up to 41 U/L in males, up to 31 U/L in females; AST = up to 37 U/L in males, up to 31 U/L in females; ALP = 22–92 U/L; PT-INR = 1; total bilirubin = up to 1 mg/dL; albumin = 3.8–5.4 g/dL; platelet count = 150–400 × 109/L.
Student t test.
Mann–Whitney U test.