Table 1.
Characteristics* | Male (N = 322) | Female (N = 309) | Total (N = 631) |
---|---|---|---|
Age (years), mean ± SD | 2.4 ± 1.2 | 2.4 ± 1.3 | 2.4 ± 1.3 |
Hb count (g/dL) | 11.9 ± 1.3 | 12.0 ± 1.2 | 11.9 ± 1.3 |
Ethnicity | |||
Banyankole | 275 (85.4) | 256 (82.9) | 531 (84.2) |
Bakiga | 29 (9.1) | 34 (11.0) | 63 (10.0) |
Baganda | 11 (3.4) | 11 (3.6) | 22 (3.5) |
Other | 7 (2.2) | 8 (2.6) | 15 (2.4) |
Microscopy-confirmed malaria infection | 10 (3.1) | 12 (3.9) | 22 (3.5) |
G6PD deficient by CareStart™ G6PD RDT† | 35 (10.9) | 19 (6.2) | 54 (8.6) |
WHO classification of deficiency | |||
Moderate (10% to < 30%) | 5 (1.6) | 5 (1.6) | 10 (1.6) |
Mild (30% to < 60%) | 20 (6.2) | 13 (4.2) | 33 (5.2) |
Normal (≥ 60%) | 297 (92.2) | 291 (94.2) | 588 (93.2) |
G6PD 202A genotype (N = 625)‡ | |||
Wild-type female | – | 272 (88.6) | 272 (43.5) |
Heterozygous female | – | 31 (10.1) | 31 (5.0) |
Homozygous mutant female | – | 4 (1.3) | 4 (0.6) |
Wild-type male | 293 (92.1) | – | 293 (46.9) |
Hemizygous male | 25 (7.9) | – | 25 (4.0) |
G6PD = glucose-6-phosphate dehydrogenase; Hb = hemoglobin; SD = standard deviation; WHO = World Health Organization.
Values are mean ± SD for continuous variables and n (column %) for categorical variables.
Deficiency defined as no background color in result window.
Dried blood spots were available for only 625 participants.