Figure.

Panel A: Proportion of patients with negative cultures (white), positive cultures able to guide de-escalation of antibiotics (dark grey), and positive cultures not able to allow de-escalation (shaded gray) in the de-escalation and continuation arms of therapy with anti-pseudomonal beta-lactam antibiotics. Panel B: Cumulative incidence frequencies of emergence of resistant pathogens by day 14. Results shown for the overall groups and for the subgroup with positive cultures. Cumulative incidence frequencies for the culture positive subgroup were extracted from Supplementary Figure 2c of [1] after digitization.