Table 1.
Characteristics of Some Devices for Continuous Glucose Monitoring.
| Company name | Product name | Regulatory status—hospital use | Sample location | Glucose source | Sensor location | Measurement method | Measurement frequency |
|---|---|---|---|---|---|---|---|
| Edwards Lifesciences | GlucoClear | CE mark (commercialization paused) | Catheter in peripheral vein | Venous blood | Sensor in catheter lumen | Electrochemical/enzymatic | 5 min |
| International Biomedical | GlucoScout | FDA approved No CE mark |
Catheter in peripheral vein, central vein, or radial artery | Venous or arterial blood | External sensor with tubing | Electrochemical/enzymatic | 5 to 60 min |
| B. Braun | ? | Pending | Catheter in peripheral vein, central vein, or radial artery | Venous or arterial blood | External sensor with tubing | NIR absorption spectroscopy, electrochemical/enzymatic | 5 to 60 min |
| Cascade Matrix | CMI System | Pending | Catheter in peripheral vein, central vein, or radial artery | Venous blood | External sensor with tubing | NIR absorption spectroscopy, electrochemical/enzymatic | 5 to 60 min |
| Optiscan | Optiscanner | CE mark | Catheter in central vein | Venous blood transformed into plasma | External sensor with tubing | MIR absorption Spectroscopy |
15 min |
| Medtronic (GluMetrics) | GluCath | Pending | Optical fiber in radial artery, peripheral vein, or central vein | Venous or arterial blood | Sensor in artery or vein lumen | Boronic acid Quenched fluorescence |
1 to 5 min |
| GlySure | GlySure CGMS |
CE mark | Optical fiber in central vein | Venous or arterial blood | Sensor in artery or vein lumen | Diboronic acid Quenched fluorescence |
1 to 5 min |
| GlucoSet | GlucoSet CGMS |
Pending | Optical fiber in radial artery, peripheral vein, or central vein | Venous or arterial blood | Sensor in artery or vein lumen | Boronic acid, change in hydrogel volume | 1 to 5 min |
| Flowsion | Diramo System | Pending | Microdialysis catheter in central vein | Dialysate from venous or arterial blood | External sensor with tubing | Quenched fluorescence | 5 to 10 min |
| Maquet Critical Care | Eirus System | CE mark | Microdialysis catheter in central vein, peripheral vein, or radial artery | Dialysate from venous or arterial blood | External sensor with tubing | Electrochemical/enzymatic | 5 to 10 min |
| Probe Scientific | MicroEye | Pending | Microdialysis catheter in central vein, peripheral vein, or radial artery | Dialysate from venous or arterial blood | External sensor with tubing | Electrochemical/enzymatic | 5 to 10 min |
| A. Menarini Diagnostics | GlucoDay | Pending for blood | Microdialysis catheter in central vein, peripheral vein, or radial artery | Dialysate from venous or arterial blood | External sensor with tubing | Electrochemical/enzymatic | 5 to 10 min |
| A. Menarini Diagnostics | GlucoDay | CE mark for ISF | Microdialysis catheter in subcutaneous tissue | Dialysate from interstitial fluid | Sc tissue | Electrochemical/enzymatic | 5 min |
| Roche Diagnostics | Seven Plus | Pending | Electrochemical electrode in subcuntaneous tissue | Interstitial fluid | Sc tissue | Multiple electrodes Electrochemical/enzymatic/fluorescence |
1 min |
| Medtronic MiniMed | Sentrino | CE mark (commercialization paused) |
Electrochemical electrode in subcuntaneous tissue | Interstitial fluid | Sc tissue | Multiple electrodes Electrochemical/enzymatic |
1 min |
| DexCom | DexCom G4 | CE marked and FDA approved for management of diabetes | Electrochemical electrode in subcutaneous tissue | Interstitial fluid | Sc tissue | Electrochemical/enzymatic | 5 min |
| Abbott Diabetes | Navigator II | CE marked for management of diabetes | Electrochemical electrode in subcutaneous tissue | Interstitial fluid | Sc tissue | Electrochemical/enzymatic | 1 min |
| EchoTherapeutics | Symphony tCGM System | Pending | Electrochemical electrode on skin surface; noninvasive | Transdermal interstitial fluid | Skin surface | Electrochemical/enzymatic | 1 min |
Information was up to date at the time of publication.