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. Author manuscript; available in PMC: 2016 Nov 3.
Published in final edited form as: Biochem Biophys Res Commun. 2015 Apr 23;461(4):648–652. doi: 10.1016/j.bbrc.2015.04.082

Figure 2. Structures of SECIS elements of T. denticola Trx1 and E. coli formate dehydrogenase H.

Figure 2

The SECIS of T. denticola Trx1 contains a conserved G nucleotide (bold) in the apical loop, but lacks a bulged U, which is present in the minimal step-loop structure (boxed) in E. coli formate dehydrogenase H (FdhH) SECIS. Sec UGA codons are shown in italics and numbering of nucleotides is stated at these Sec codons. The SECIS structure of T. denticola Trx1 was predicted using RNAfold [24].