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PDA cell proliferation and response to gemcitabine on native and TG2-cross-linked collagen. (A) Relative proliferation of AsPC1 cells cultured on native collagen, TG2-mediated cross-linked collagen, or uncoated plates for 48 hours. (B) Relative proliferation of AsPC1 cells cultured on native collagen, TG2-mediated cross-linked collagen, or uncoated plates and treated with different doses of gemcitabine for 48 hours. Bars represent average measurements ± SE. *P < .05.
