Table 3.

Adipokines and insulin levels as a function of the MS score

	MS score					P-value
	0 (n = 6)	1 (n = 25)	2 (n = 47)	3 (n = 39)	4 (n = 25)
GFR-epia	48.1 ± 16.1	35.2 ± 24.7	36.5 ± 18.5	36.9 ± 18.8	25.6 ± 10.4b,c,d
Leptin	8.5 ± 16.5	9.5 ± 22.3	23.1 ± 34.4e	42 ± 37b,c,e	47.3 ± 38.4b,c,e	<0.001
TAdip	8.8 ± 6.1	14.3 ± 6.5b	10.5 ± 5.5e	8.8 ± 4e	10 ± 6.9e	0.006
HMWAdip	4.3 ± 4.1	7.8 ± 4.6b	5.3 ± 3.6e	4.1 ± 2.4e	5.8 ± 6e	0.014
Insulin	14.8 ± 9.9	17.1 ± 13.8	25.8 ± 22.2e	37.2 ± 26.6b,c,e	38.9 ± 22.9b,c,e	<0.001

^aCalculated for patients at CKD stages 2–5 (n = 96). For units, please see Table 2.

^b0 versus 1, 3, 4, P < 0,05.

^c2 versus 3, 4, P < 0,05.

^d3 versus 4, P < 0,05.

^e1 versus 2, 3, 4, P < 0,05;

GFR, glomerular filtration rate; TAdip, total adiponectin; HMWAdip, high-molecular weight adiponectin.