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CCND1 silencing inhibited proliferation and led to G1 cell cycle arrest in ESCC cells. (A and B) The knockdown of CCND1 inhibits cell proliferation in YSE30 and KYSE510 cells. (C and D) The knockdown of CCND1 induces G1 cell cycle arrest in YSE30 and KYSE510 cells. (E) Model diagram indicating the regulation mechanism of HOTAIR in ESCC. *P < .05.
