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. 2016 Oct 28;9(6):498–504. doi: 10.1016/j.tranon.2016.10.002

Figure 1.

Figure 1

The specificity and activity on cell proliferation of HPV16-E6/E7- CRISPR/Cas9. Transfection of HPV-16-E6/E7-CRISPR/Cas9 did not affect proliferation of HPV-negative C33-A cervical cancer cells, while the proliferation was severely inhibited by transfection of either HPV-16-E6-CRISPR/Cas9 or HPV-16-E7-CRISPR/Cas9. The figures are representative of three independent experiments. Data represent the mean of three impendent experiments ± SE. The asterisk represents statistically significant difference compared with negative control (*P < .05; **P < .01).