Table 2. Results of hydrate screening experiments that afforded anhydrous (A) and/or hydrated (H) forms.
| Compound | Slurry in H2O | 75% R.H./40°C | Competitive slurry | SDG† | Hydrate stability in air |
|---|---|---|---|---|---|
| 1 | A | A | – | A | – |
| 2 | A | A | – | A | – |
| 3 | A | A | – | A | – |
| 4 | H | H | H | H | > 30 d |
| 5 | H | H | H | A + H | 10 d < H < 30 d |
| 6 | H | H | H | A + H | > 30 d |
| 7 | H | H | H | A + H | < 1 d |
| 8 | H | H | H | A | < 1 d |
| 9 ‡ | H | H | H | – | – |
| 10 | H | H | H | A + H | < 1 d |
| 11 | H | H | H | A + H | > 30 d |
†
For compounds 1–3, SDG was performed for 30 min each.
‡
Experiments to determine the stability of the hydrate of 9 were not performed due to the similarity of the powder patterns of the hydrated and the anhydrous forms.