Table 3.
Univariable analysis of prognostic factors associated with 5-year overall survival of 82 patients with large hepatocellular carcinoma who underwent hepatic resection
| Variable | No of survival | No of death | P value | |
|---|---|---|---|---|
| Gender | Male/female | 29/4 | 44/5 | 0.713 |
| Age (years) | ≥60/<60 | 7/26 | 15/34 | 0.403 |
| Tumor size (cm) | >10/≤10 | 5/28 | 14/35 | 0.057 |
| Hepatitis status | HBsAg (+)/(−) | 26/7 | 40/8 | 0.850 |
| Liver cirrhosis | Present/absent | 26/7 | 39/10 | 0.985 |
| AFP (ug/L) | ≥400/<400 | 7/26 | 28/21 | 0.018 |
| HR type | Major/minor | 7/26 | 19/30 | 0.486 |
| Vascular clamping | Yes/no | 29/4 | 42/7 | 0.591 |
| Perioperative transfusions | Yes/no | 18/15 | 28/21 | 0.975 |
| Number of tumor | Solitary/multiple | 29/4 | 39/10 | 0.286 |
| Tumor capsule | Present/absent | 23/10 | 25/24 | 0.032 |
| Microvascular invasion | Present/absent | 6/27 | 13/36 | 0.051 |
| Grade of differentiation | Poor and moderate/well | 24/9 | 46/3 | 0.001 |
| Spontaneous tumor rupture | Present/absent | 3/30 | 9/40 | 0.029 |
| Complications | Present/absent | 11/22 | 27/22 | 0.419 |
| Tumor recurrence | Yes/no | 7/26 | 43/6 | 0.000 |
HBsAg, hepatitis B virus surface antigen; AFP, α-fetoprotein; HR, hepatic resection.