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. 2016 Jun 29;30(4):1099–1111. doi: 10.1111/jvim.14364

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Copyright © 2016 The Authors. Journal of Veterinary Internal Medicine published by Wiley Periodicals, Inc. on behalf of the American College of Veterinary Internal Medicine.

This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.

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Immunohistochemistry for endothelin‐1 of canine liver (A) and spinal cord (B–D) tissue. A—Marked immunostaining of bile duct in liver serving as positive control (IHC, bar = 50 μm); B—Spinal cord white matter with strongly stained astrocytes (arrows) and a small capillary with positively stained endothelial cells (arrowhead) (IHC, bar = 50 μm); C—Severely necrotic area in the center of the lesion with small vessels with positively stained endothelial cells (arrows) (IHC, bar = 20 μm); and D—Positively stained macrophages (arrows) (IHC, bar = 20 μm).