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. 2016 Jun 28;30(4):1313–1321. doi: 10.1111/jvim.14371

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Copyright © 2016 The Authors. Journal of Veterinary Internal Medicine published by Wiley Periodicals, Inc. on behalf of the American College of Veterinary Internal Medicine.

This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.

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Immune‐mediated myositis (IMM) horse 2. (A) Major histocompatibility complex (MHC) I staining of mononuclear infiltrates that is so dense it obscures potential sarcolemmal MHC I staining. (B) MHC II staining of mononuclear infiltrates without evident MHC II sarcolemmal staining. (C) Immunohistochemical (IHC) staining of numerous CD4+ lymphocytes in the endomysium and within myofibers. (D) IHC staining of CD8+ lymphocytes in the endomysium. (E) IHC staining of a few CD20+ lymphocytes scattered in the endomysium. (F) Acid phosphatase staining of numerous macrophages (red aggregates) infiltrating myofibers.