Table 1.
Patient and procedure related characteristics | Baseline characteristicsa
|
Variable completeness
|
||||
---|---|---|---|---|---|---|
CAG | PCI | Surgery | CAG | PCI | Surgery | |
Number of patients | 249,445 | 100,609 | 55,539 | 249,445 | 100,609 | 55,539 |
Age, years | 63.8 (12.0) | 64.5 (11.7) | 65.8 (11.4) | 100 | 100 | 100 |
Male sex, n (%) | 23,0728 (66.0) | 72,595 (72.2) | 40,924 (73.7) | 100 | 100 | 100 |
Height, cm | 172.3 (9.5) | 173.1 (9.2) | 172.6 (9.2) | 57.1 | 54.5 | 47.9 |
Weight, kg | 81.0 (17.4) | 81.8 (16.5) | 80.8 (16.1) | 57.6 | 54.9 | 48.2 |
Smoking status (current or former), n (%) | 154,536 (62.0) | 64,990 (64.6) | 30,021 (54.1) | 90.2 | 86.7 | 80.9 |
Diabetes (with or without treatment), n (%) | 33,275 (13.3) | 12,739 (12.7) | 7,940 (14.3) | 93.6 | 89.6 | 85.0 |
Left ventricular ejection fraction | 53.4 (13.7) | 52.8 (13.1) | – | 47.0 | 40.2 | – |
Cardiac centers | – | – | – | 100 | 100 | 100 |
Clinical presentation | – | – | – | 92.4 | 92.5 | – |
Acute, n (%) | 42,787 (17.2) | 33,012 (32.8) | – | – | – | – |
Subacute, n (%) | 46,761 (18.7) | 19,758 (19.6) | – | – | – | – |
Elective, n (%) | 140,821 (56.5) | 40,318 (40.1) | – | – | – | – |
Unknown, n (%) | 19,076 (7.6) | 7,521 (7.5) | – | – | – | – |
Indication | 92.7 | 87.9 | – | |||
STEMI, n (%) | 31,693 (12.7) | 24,091 (23.9) | – | – | – | – |
NSTEMI/UAP, n (%) | 58,787 (23.6) | 25,433 (25.3) | – | – | – | – |
Stable angina, n (%) | 80,978 (32.5) | 29,678 (29.5) | – | – | – | – |
Other, n (%) | 59,721 (23.9) | 9,208 (9.2) | – | – | – | – |
Unknown, n (%) | 18,266 (7.3) | 12,199 (12.1) | – | – | – | – |
Referral date | – | – | – | 98.1 | 94.7 | 61.9 |
Procedure date | – | – | – | 100 | 100 | 100 |
Procedure codes (NCSP)b | – | – | – | 62.7 | 81.9 | 50.7 |
Catheter size, Fr | 5.9 (0.4) | 6.0 (6.0, 6.0) | – | 61.6 | 61.3 | – |
Contrast volume, mL | 70.0 (50.0, 100.0) | 100.0 (70.0, 170.0) | – | 62.5 | 62.3 | – |
Fluoroscopy time, min | 2.0 (1.0, 4.0) | 6.70 (3.0, 12.0) | – | 99.2 | 99.1 | – |
X-ray dose, Gy cm2 | 25.0 (14.0, 44.0) | 41.0 (20.0, 79.0) | – | 98.4 | 98.7 | – |
CAD severity | – | – | – | – | 50.5 | – |
1-vessel disease, n (%) | 49,691 (19.9) | – | – | – | – | – |
2-vessel disease, n (%) | 13,706 (5.5) | – | – | – | – | – |
3-vessel disease, n (%) | 15,384 (6.2) | – | – | – | – | – |
Diffuse CAD, n (%) | 17,833 (7.1) | – | – | – | – | – |
Normal, n (%) | 29,414 (11.8) | – | – | – | – | – |
Unknown, n (%) | 123,417 (49.5) | – | – | – | – | – |
Number of stents | – | 1.0 (1.0, 2.0) | – | – | 61.7 | – |
Number of treated lesions | – | 1.0 (1.0, 2.0) | – | – | 99.5 | – |
Number of treated arteries | – | – | – | – | 77.7 | – |
1 vessel, n (%) | – | 65,844 (65.4) | – | – | – | – |
2 vessels, n (%) | – | 11,123 (11.1) | – | – | – | – |
3 vessels, n (%) | – | 1,203 (1.2) | – | – | – | – |
Unknown, n (%) | – | 22,439 (22.3) | – | – | – | – |
Local vascular complications, n (%) | 3,516 (1.4) | 1,625 (1.6) | – | 77.5 | 80.0 | – |
Emergency CABG surgery, n (%) | 1,555 (0.6) | 422 (0.4) | – | 60.7 | 60.5 | – |
Surgery | – | – | 99.2 | |||
Isolated CABG, n (%) | – | – | 31,663 (57.0) | – | – | – |
Isolated valve surgery, n (%) | – | – | 12,011 (21.6) | – | – | – |
CABG and valve surgery, n (%) | – | – | 4,622 (8.3) | – | – | – |
Other, n (%) | – | – | 6,801 (12.2) | – | – | – |
Unknown, n (%) | – | – | 442 (0.8) | – | – | – |
Valvular surgery | ||||||
Aortic, n (%) | – | – | 9,495 (17.1) | – | – | 100 |
Mitral, n (%) | – | – | 2,694 (4.9) | – | – | 100 |
Tricuspid, n (%) | – | – | 303 (0.6) | – | – | 59.7 |
Pulmonary, n (%) | – | – | 145 (0.3) | – | – | 59.7 |
EuroSCORE | – | – | 5.2 (3.5) | – | – | 95.3 |
Extracorporal circulation, n (%) | – | – | 43,168 (77.7) | – | – | 97.0 |
ICU length of stay, hours | – | – | 22.0 (20.0, 24.0) | – | – | 86.0 |
Reoperation for bleeding, n (%) | – | – | 3,124 (5.6) | – | – | 94.1 |
Deep sternal wound infection, n (%) | – | – | 549 (1.0) | – | – | 92.4 |
Procedure-related myocardial infarction, n (%) | 1,619 (0.6)c | 513 (0.5)c | 1,713 (3.1)d | 79.4 | 80.1 | 91.3 |
Procedure-related stroke, n (%) | 278 (0.1)c | 353 (0.4)c | 847 (1.5)e | 62.6 | 62.3 | 91.2 |
Vital status | – | – | – | 98.3 | 98.1 | 98.3 |
Notes:
Continuous variables are presented as means (SD) or medians (interquartile range), and categorical variables are presented as numbers (%).
NCSP codes are used to classify each procedure: CAG (UXAC40, UXAC85, UXAC90, UXUC85-UXUC87, UFYA20), PCI (KFNG00, KFNG02, KFNG05, KFNG10, KFNG12, KFNG20, KFNG22, KFNG30, KFNG40, KFNG96, KZFX01), CABG (KFNA-F, KFNH, KFNJ, KFNK, KFNW), valve surgery (KFG, KFK, KFJE, KFJF, KFM).
Within 12 hours,
during admission,
onset of symptoms within 12 hours and lasting >24 hours.
Abbreviations: CAG, coronary angiography; PCI, percutaneous coronary intervention; STEMI, ST-segment elevation myocardial infarction; NSTEMI, non-ST segment elevation myocardial infarction; UAP, unstable angina pectoris; NCSP, NOMESCO classification of surgical procedures; Fr, the French scale; CAD, coronary artery disease; CABG, coronary artery bypass grafting; EuroSCORE, European System for Cardiac Operative Risk Evaluation; ICU, intensive care unit; SD, standard deviation.