General staging: |
Computed tomography scan and tumor markers (α-fetoprotein, human chorionic gonadotropin, lactate dehydrogenase) |
Stage I: |
Tumor in one or both testicles |
Treatment |
All patients followed on a surveillance program |
Metastatic disease |
Divided according to prognostic factors into a good, intermediate, and poor risk group |
Treatment |
Radiotherapy for stage IIa and IIb seminoma with lymph nodes <3 cm. |
Three or four cycles of cisplatin, etoposide, and bleomycin for all other patients |
Risk factors |
Histology, tumor markers, metastases outside lung and lymph nodes, extragonadal tumors in mediastinum of nonseminoma origin |