Table 3. Comparison of maternal age-specific rates for common autosomal trisomies (trisomies 21, 18 and 13) and aneuploidies per 1,000 fetuses and live births in various age groups from various studies.

Maternal age	Fetus rate at the time of amniocentesis						Live births rate at the time of delivery
	This study	Hook 1983 [4]	Ferguson-Smith 1984 [5]	Yaegashi 1998 [6]	Park 2010 [7]	Kim 2013 [8]a	Savva 2010 [15]
	T21, T13, T18	T21, T13, T18	T21, T13, T18	T21, T13, T18	All aneuploidies	T21, T13, T18	T21, T18, T13
34	4.54	4.30	N/A	N/A	N/A	N/A	1.83
35	4.61	5.50	4.50	3.94	7.92	11.14	2.22
36	5.71	7.10	5.90	5.13	10.06	13.15	2.81
37	7.84	8.90	7.70	6.64	12.79	15.54	3.64
38	11.01	11.50	10.00	8.6	16.26	18.35	4.85
39	15.22	14.70	13.20	11.15	20.67	21.68	6.53
40	20.46	18.80	17.20	14.45	26.28	25.62	8.78
41	26.73	24.00	22.50	18.73	33.41	30.28	11.67
42	34.04	30.60	29.40	24.31	42.47	35.80	15.18
43	42.39	39.20	36.00	31.55	53.99	42.34	19.18
44	51.77	50.30	40.90	40.96	68.63	50.08	23.47
45	62.19	64.40	50.60	53.19	87.25	59.26	27.79
46	73.64	82.5	62.80	N/A	N/A	70.13	31.90
47	86.14	105.8	28.6	N/A	N/A	83.04	35.65
48	99.66	135.6	28.6	N/A	N/A	N/A	38.91
Sample size	17,819	N/A	52,965	5,484	2,032	5,055	4.5 million
Study location	Thailand	Mixed	Europe	Japan	Korea	Korea	Mixed

T21: trisomy 21, T18: trisomy 18, T13: trisomy 13, N/A: not available.

^aAge at the time of delivery.