Table 2. Detection of viral antigen by IHC in cells in the nasal cavity and lung of hamsters inoculated with NiV-M.

Cell Types	Time Post Inoculation (Hours)
	4				8				16				24				32				48
Nasal Cavity
Respiratory epithelium	-	-	-	-	-	-	-	-	+	-	-	+	+	-	NE1	++	++	+	+	-	++	++	++	+
Olfactory epithelium	-	-	-	-	-	-	-	-	-	-	-	++	++	-	NE	++	++	++	-	-	+++	-	++++	+
Submucosal gland epithelium	-	-	-	-	-	-	-	-	-	-	-	-	-	-	NE	++	++	-	-	-	++	-	+++	-
Lung
Type I pneumocytes	-	-	-	-	++	-	++	-	++	-	+++	-	-	++	-	-	-	+++	-	+++	++++	-	++	-
Alveolar macrophages	-	-	-	-	++	-	++	-	++	-	+++	-	-	++	-	-	+	+++	-	+++	++++	-	++	-
Bronchiolar respiratory epithelium	-	-	-	-	+	-	+++	-	++	-	+++	-	-	+++	-	-	++	+++	-	+++	+++	-	++	-
Bronchiolar smooth muscle	-	-	-	-	-	-	-	-	-	-	+	-	-	-	-	-	-	-	-	-	++	-	-	-
Bronchial respiratory epithelium	-	-	-	-	-	-	-	-	++	-	++	-	-	+++	-	-	++	++	-	+++	+++	-	+++	-
Arterial smooth muscle	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	++	+	-	-	-

Each column represents a single hamster.

The columns representing individual hamsters in this table correspond to the columns in Table 1.

The presence of Nipah virus antigen, as detected by IHC, was graded in cell types in the nasal cavity and lung.

Grading scale: -, negative; +, focal immunopositivity; ++, multifocal mild immunopositivity; +++, multifocal moderate immunopositivity; ++++, multifocal to diffuse marked immunopositivity.

¹Not examined (NE). The cell type was not present in the tissue section examined.