Table 2. nDNA SNPs that associate with the African-Caucasian differences in mtDNA expression from the long RNA dataset.
Chromosome | SNP accession number | nDNA Gene | SNP location in the nDNA gene | mtDNA gene with altered expression | *p-value |
7 | rs28495024 | PTCD1 | UTR-3 | ND2 | 4.84e-8 |
7 | rs28495024 | PTCD1 | UTR-3 | CO2 | 3.86e-7 |
7 | rs2003499 | PTCD1 | UTR-3 | CO2 | 2.89e-6 |
17 | rs16967742 | MRPS7 | UTR-5 | ND2 | 8.38e-7 |
17 | rs16967742 | MRPS7 | UTR-5 | CO2 | 4.36e-6 |
2 | rs6739788 | PNPT1 | UTR-3 | CO2 | 2.11e-6 |
2 | rs7594497 | PNPT1 | Exon N>D | CO1 | 2.41e-6 |
2 | rs7594497 | PNPT1 | Exon N>D | CO2 | 3.14e-6 |
3 | rs667894 | HEMK1 | UTR-3 | ND2 | 2.38e-6 |
3 | rs667894 | HEMK1 | UTR-3 | CO1 | 4.02e-6 |
3 | rs667894 | HEMK1 | UTR-3 | CO2 | 2.71e-6 |
3 | rs667894 | HEMK1 | UTR-3 | ND6 | 5.27e-6 |
4 | rs10938024 | GRSF1 | UTR-3 | ND2 | 2.90e-6 |
4 | rs7694924 | GRSF1 | UTR-3 | ND2 | 5.12e-6 |
*P-values were calculated using the Matrix eQTL R-package.