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. 2016 Nov 3;11(11):e0165672. doi: 10.1371/journal.pone.0165672

Table 1. Baseline characters.

Variables Fibrinolysis (N = 160) Primary PCI (N = 1000) No reperfusion (N = 1922) P value
Age (year) 78.79 ±7.12 79.59 ±4.04 80.59 ±4.57 <0.001
Male 100 (62.5%) 643 (64.3%) 1086 (56.5%) <0.001
Time from symptom onset to treatment <0.001
<3 h 51 (31.9%) 278 (27.8%) 246 (12.8%)
3–6 h 61 (38.1%) 372 (37.2%) 344 (17.9%)
6–12 h 19 (11.9%) 229 (22.9%) 264 (13.7%)
12–24 h 11 (6.9%) 56 (5.6%) 285 (14.8%)
1–7 d 18 (11.3%) 65 (6.5%) 783 (40.7%)
Hospital level <0.001
Province level 18 (11.3%) 449 (44.9%) 404 (21.0%)
Municipal level 81 (50.6%) 509 (50.9%) 1082 (56.3%)
Tertiary level 61 (38.1%) 42 (4.2%) 436 (22.7%)
Medical history
Prior MI 14 (8.8%) 54 (5.4%) 135 (7.0%) 0.127
Prior CABG 1 (0.6%) 3 (0.3%) 5 (0.3%) 0.767
Prior PCI 6 (3.8%) 41 (4.1%) 57 (3.0%) 0.272
Prior stroke 26 (16.3%) 98 (9.8%) 258 (13.4%) 0.005
Prior HF 6 (3.8%) 21 (2.1%) 70 (3.6%) 0.057
PAD 0 (0.0%) 7 (0.7%) 14 (0.7%) 0.324
Prior bleeding 1 (0.6%) 18 (1.8%) 50 (2.6%) 0.096
CKD 1 (0.6%) 11 (1.1%) 30 (1.6%) 0.387
Risk factors
Diabetes 25 (15.6%) 170 (17.0%) 326 (17.0%) 0.904
Hypertension 95 (59.4%) 563 (56.3%) 1063 (55.3%) 0.570
Dislipidemia 6 (3.8%) 66 (6.6%) 44 (2.3%) <0.001
Currently Smoking 66 (41.3%) 389 (38.9%) 664 (34.5%) 0.028
Admission presentation
LVEF (%) 52 [48.5, 55] 52 [48, 58] 52 [47, 54] <0.001
Heart rate (bpm) 73 [62.5 84.5] 74 [63, 85] 79 [67, 92] <0.001
SBP (mmHg) 124.5 [110, 142.5] 125 [110, 142] 127 [110, 144] 0.556
DBP (mmHg) 75 [65, 88.5] 75 [64, 83] 75 [65, 85] 0.689
Killip classification <0.001
I 100 (62.5%) 718 (71.8%) 1062 (55.3%)
II 33 (20.6%) 214 (21.4%) 513 (26.7%)
III 15 (9.4%) 29 (2.9%) 204 (10.6%)
IV 12 (7.5%) 39 (3.9%) 143 (7.4%)
GRACE score <0.001
Very high risk 107 (66.9%) 659 (65.9%) 1456 (75.8%)
Moderate high risk 50 (31.3%) 333 (33.3%) 452 (23.5%)
Low risk 3 (1.9%) 8 (0.8%) 14 (0.7%)

MI, myocardial infarction; CABG, Coronary artery bypass graft; PCI, percutaneous coronary intervention; HF, heart failure; PAD, Peripheral artery disease; CKD, chronic kidney disease; LVEF, left ventricular ejection fraction; SBP, systolic blood pressure; DBP, diastolic blood pressure;