Table 4. Odds ratio (95% confidence interval) of incident cognitive impairment according to baseline 25-hydroxyvitamin D concentrations modeled as race-specific tertiles and stratified by race.
25(OH)D Tertile 1> 23 ng/ml for blacks> 32 ng/ml for whites | 25(OH)D Tertile 215–23 ng/ml for blacks25-32 ng/ml for whites | 25(OH)D Tertile 3< 15 ng/ml for blacks< 25 ng/ml for whites | |
---|---|---|---|
Black participants | |||
Events | 31 | 69 | 53 |
Model 1 | ref | 2.79 (1.64,4.76) | 2.19 (1.26,3.83) |
Model 2 | ref | 2.74 (1.48,5.07) | 1.93 (0.98,3.79) |
Model 3 | ref | 2.96 (1.48,5.94) | 2.40 (1.07, 5.40) |
White participants | |||
Events | 105 | 97 | 119 |
Model 1 | ref | 0.94 (0.64,1.38) | 1.35 (0.92,1.96) |
Model 2 | ref | 1.01 (0.66,1.56) | 1.23 (0.79,1.90) |
Model 3 | ref | 1.12 (0.70,1.78) | 1.22 (0.76, 1.96) |
25(OH)D, 25-hydroxyvitamin D; Model 1 is unadjusted; Model 2 is adjusted for geographic region of residence, season of blood draw, annual income, diabetes status, history of coronary heart disease, current smoking and depressive symptoms; Model 3 is adjusted for variables in model 2 plus estimated glomerular filtration rate, log-transformed albumin to creatinine ratio, phosphorus, calcium, and parathyroid hormone