Skip to main content
. 2016 Nov 3;11(11):e0165483. doi: 10.1371/journal.pone.0165483

Table 1. The expression profiles of genes in HFD, HFD + DSHT, or HFD + ORL-treated mice which were significantly up-regulated in HFD-fed animals by 2 folds.

Gene name Protein HFD DSHT ORL
Apoa2 Apolipoprotein A-II 2.3784 1.1173 1.4208
Apoa4 Apolipoprotein A-IV 3.7842 1.5692 1.2541
Apod Apolipoprotein D 3.5554 0.6783 0.9571
Apol8 Apolipoprotein L 8 4.084 0.8066 1.0994
Cyp11a1 Cytochrome P450, family 11, subfamily a, polypeptide 1 6.5432 1.2483 1.7613
Cyp46a1 Cytochrome P450, family 46, subfamily a, polypeptide 1 6.1475 0.9461 1.0767
Cyp51 Cytochrome P450, family 51 2 4.5631 2.6882
Dhcr24 24-dehydrocholesterol reductase 2.514 1.2397 1.3535
Dhcr7 7-dehydrocholesterol reductase 4.9246 2.042 2.1535
Fdps Farnesyl diphosphate synthetase 4.7899 3.605 1.9543
Hmgcs1 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 8.6939 6.2767 3.1529
Ldlr Low density lipoprotein receptor 4.0278 1.4948 2.0658
Lep Leptin 6.5432 1.7777 1.7613
Lipe Lipase, hormone sensitive 2.5315 1.3104 1.7013
Lrp1b Low density lipoprotein-related protein 1B (deleted in tumors) 3.1602 6.9163 1.5547
Mvd Mevalonate (diphospho) decarboxylase 5.0982 4.9588 2.7638
Mvk Mevalonate kinase 3.5064 2.4794 2.4566
Npc1l1 NPC1-like 1 10.9283 1.2483 1.7613
Nr0b2 Nuclear receptor subfamily 0, group B, member 2 1.9185 1.257 0.9374
Olr1 Oxidized low density lipoprotein (lectin-like) receptor 1 5.9381 1.2397 0.8868
Osbpl5 Oxysterol binding protein-like 5 4.3469 0.5824 1.5655
Pcsk9 Proprotein convertase subtilisin/kexin type 9 2.2346 3.0951 2.1238
Pmvk Phosphomevalonate kinase 3.249 1.1567 1.2368
Ppard Peroxisome proliferator activator receptor delta 3.8106 1.1487 1.4306
Prkaa2 Protein kinase, AMP-activated, alpha 2 catalytic subunit 2.0279 1.2834 1.2198
Scarf1 Scavenger receptor class F, member 1 2.1287 1.2226 1.0693
Soat1 Sterol O-acyltransferase 1 1.9319 0.9138 1.3629
Sorl1 Sortilin-related receptor, LDLR class A repeats-containing 2.2501 1.4948 1.5764
Srebf1 Sterol regulatory element binding transcription factor 1 2.0279 1.0943 1.9408
Stard3 START domain containing 3 2.114 0.9526 1.1783