. Author manuscript; available in PMC: 2016 Nov 3.

Published in final edited form as: Am J Orthod Dentofacial Orthop. 2012 Nov;142(5):662–670. doi: 10.1016/j.ajodo.2012.06.014

Table IV.

Association of different haplotypes with annual jaw growth

	Boys				Girls
Haplotype	Annual Mx growth (mm)	P value	Annual Md growth (mm)	P value	Annual Mx growth (mm)	P value	Annual Md growth (mm)	P value
Haplotype 1		< 0.0001^*		< 0.0001^*		0.7378		0.9481

0	1.8 (0.1)a		2.5 (0.2)a		1.9 (0.2)a		2.8 (0.2)a

1	2.3 (0.1)b		3.4 (0.2)b		1.7 (0.1)a		2.9 (0.2)a

2	2.8 (0.1)c		4.3 (0.2)c		1.7 (0.2)a		2.8 (0.2)a

Haplotype 2		0.1203		0.0002^*		0.7448		0.9760

0	2.5 (0.1)a		4.0 (0.2)a		1.7 (0.2)a		2.8 (0.2)a

1	2.1 (0.1)a		3.1 (0.1)b		1.8 (0.1)a		2.8 (0.2)a

2	2.0 (0.3)a		2.2 (0.4)c		1.8 (0.2)a		2.8 (0.2)a

Haplotype 3		0.0039^*		0.0837		0.9833		0.8258

0	2.3 (0.1)a		3.4 (0.2)a		1.8 (0.1)a		2.8 (0.1)a

1	1.8 (0.1)b		2.8 (0.3)a		1.7 (0.2)a		2.9 (0.3)a

Haplotype 4		0.1155		0.1259		–		–

0	2.3 (0.1)a		3.3 (0.1)a		1.8 (0.1)		2.8 (0.1)a

1	1.8 (0.4)a		2.0 (0.6)b		–		–

2	1.6 (0.3)a		3.3 (0.6)ab		–		–

Haplotype 1, T_rs2470144T_rs2445761; haplotype 2, C_rs2470144C_rs2445761; haplotype 3, C_rs2470144T_rs2445761; haplotype 4, T_rs2470144C_rs2445761. 0, 1, and 2 represent 0, 1, and 2 of this haplotype, respectively. Values of annual maxillary (Mx) and mandibular (Md) growth are presented as least square means (and standard errors). Values with no common letter (a, b, or c) for the same haplotype are significantly different at P < 0.05.

P < 0.05 indicates that genotypes of this single nucleotide polymorphism have a significant effect on annual jaw growth.