Table 3.
Linear Relationships Between pMRI and hr-pQCT Bone Structure Values With and Without Coregistration
| pMRI bone outcome | Slope, 95% CI (lower, upper) | Intercept, 95% CI (lower, upper) | R2 | p Value |
|---|---|---|---|---|
| Un-coregistered | ||||
| BV/TV | 0.484 (0.361, 0.607) | −0.119 (−0.179, −0.059) | 0.526 | <0.001 |
| Tb.Sp | 0.744 (0.576, 0.911) | 0.048 (−0.060, 0.157) | 0.586 | <0.001 |
| Tb.Sp MI | 0.970 (0.781, 1.159) | −0.075 (−0.192, 0.043) | 0.654 | <0.001 |
| Tb.Th | 0.016 (−0.039, 0.071) | 0.053 (0.022, 0.084) | 0.006 | 0.554 |
| Tb.Th MI | 0.016 (−0.04, 0.071) | 0.054 (0.023, 0.085) | 0.006 | 0.578 |
| Tb.N | 2.1 (1.4, 2.9) | 0.0 (−0.7, 0.6) | 0.376 | <0.001 |
| Coregistered | ||||
| BV/TV | 0.767 (0.568, 0.967) | −0.263 (−0.362, −0.165) | 0.514 | <0.001 |
| Tb.Sp | 1.640 (1.357, 1.924) | −0.414 (−0.575, −0.252) | 0.706 | <0.001 |
| Tb.Sp MI | 1.712 (1.419, 2.004) | −0.447 (−0.613, −0.282) | 0.710 | <0.001 |
| Tb.Th | −0.010 (−0.064, 0.044) | 0.068 (0.039, 0.097) | 0.003 | 0.700 |
| Tb.Th MI | −0.011 (−0.065, 0.044) | 0.068 (0.038, 0.098) | 0.003 | 0.700 |
| Tb.N | 2.2 (1.3, 3.0) | −0.1 (−0.9, 0.7) | 0.296 | <0.001 |
Note: Hr-pQCT bone structural variables were used as the dependent variable, and pMRI bone structure was treated as an independent variable.
Abbr: BV/TV, bone volume fraction; CI, confidence interval; hr-pQCT, high-resolution peripheral quantitative computed tomography; MI, model-independent measures; pMRI, peripheral magnetic resonance imaging; Tb.N, trabecular number; Tb.Sp, trabecular separation; Tb.Th, trabecular thickness.