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Top 2 canonical pathways of protein expressed in original patients tumors which were successfully engrafted into NSG mice (S) compared to tumors were not successfully engrafted (F)
| p-value | Overlap | ||
|---|---|---|---|
|
S vs F (ER+HER2−)
| |||
| 1. AMPK Signaling | 1.43E-10 | 4.5% | 8/179 |
| 2. PI3K/AKT Signaling | 4.26E-10 | 5.7% | 7/123 |
|
| |||
|
S vs F (ER+HER2+)
| |||
| 1. PI3K/AKT Signaling | 2.54E-13 | 7.3% | 9/123 |
| 2. Endometrial Cancer Signaling | 1.79E-12 | 13.5% | 7/52 |
