Figure 1.

Definition of a consensus adhesome. Adhesion complexes induced by the integrin ligand fibronectin were stabilised and purified (curly arrows) and their proteomes were characterised by quantitative mass spectrometry (LC–MS/MS) in multiple studies using different cell types. Integration of these datasets generated a meta-adhesome, from which a core consensus adhesome was established [15••]. Network nodes (circles) represent interacting proteins; thick node borders indicate proteins that define the axes of emergent consensus adhesome modules (labelled, right).