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. 2016 May 15;7(24):35562–35576. doi: 10.18632/oncotarget.9384

Figure 6. ALDH2 regulates expression of MCP-1 and ICAM-1 protein via JNK and P38 MAPK system in LPS-activated HUVECs.

Figure 6

A. Phosphorylation of JNK, p38 MAPK and ERK1/2 in HUVECs stimulated by Daidzin before LPS treatment. *: P < 0.05 vs control. #: P < 0.05 vs LPS treatment alone. B. MCP-1 and ICAM-1 expression after SP600125 (20μm) or SB203580 (20μm) treatment before LPS stimulation in HUVECs. Con: control; SP600125: JNK inhibitor; SB203580: P38 inhibitor. *: P < 0.05 vs control. #: P < 0.05 vs LPS+Daidzin treatment. C. Phosphorylation of JNK, p38 MAPK and ERK1/2 in HUVECs stimulated by Alda-1 before LPS treatment. *: P < 0.05 vs control. #: P < 0.05 vs LPS treatment alone. All values are expressed as means±SEM from three independent experiments.