Figure 3. Impaired glucose homeostasis in macrophage-specific Atg7KO mice under diet-induced obesity conditions.
A. Circulating blood glucose levels in Atg7KO and control mice during a 60% HFD challenge. Circulating glucose levels were monitored in 5-h-fasted (weeks 4 and 7 after HFD) mice. B. Circulating insulin levels of Atg7KO (n = 6) and control (n = 6) mice were measured using ELISA. C. GTT and D. ITT (right) results for Atg7KO (n = 8) and control (n = 6) mice.