Table 1. Relation between protein levels of ALK5-FL, ALK5-ICD, pSmad2/3, and PAI-1 and clinicopathological parameters.

	ALK5-FL			ALK5-ICD			pSmad2/3			PAI-1
Parameter	na	Mean Rank	Pb	na	Mean Rank	Pb	na	Mean Rank	Pb	na	Mean Rank	Pb
Grade
I	76	74.1		76	70.34		76	69.9		76	64.41
			0.35			0.049			0.036			<0.0001
II	78	80.81		78	84.48		78	84.9		78	90.26
TNM Stage
Early Stage
(I+II)	84	69.4		84	66.34		84	68.17		84	63.17
			0.014			0.001			0.004			<0.0001
Advanced Stage
(III+IV)	70	87.22		70	90.89		70	88.7		70	94.7
Metastasis
M0	114	74		114	71.25		114	70.1		114	70.1
			0.1			0.003			<0.0001			0.001
M1	40	87.49		40	95.31		40	98.59		40	98.59
Tumor Size (mm)
<70	77	69.42		77	71.22		77	68.92		77	67.73
			0.024			0.08			0.017			0.007
>70	77	85.58		77	83.78		77	86.08		77	87.27

^aNumber of patients

^bGroups were compared using Mann-Whitney U-test (Significant at P < 0.05)