Skip to main content
. 2016 May 4;7(24):35917–35931. doi: 10.18632/oncotarget.9177

Table 1. Relation between protein levels of ALK5-FL, ALK5-ICD, pSmad2/3, and PAI-1 and clinicopathological parameters.

ALK5-FL ALK5-ICD pSmad2/3 PAI-1
Parameter na Mean Rank Pb na Mean Rank Pb na Mean Rank Pb na Mean Rank Pb
Grade
I 76 74.1 76 70.34 76 69.9 76 64.41
0.35 0.049 0.036 <0.0001
II 78 80.81 78 84.48 78 84.9 78 90.26
TNM Stage
Early Stage
(I+II) 84 69.4 84 66.34 84 68.17 84 63.17
0.014 0.001 0.004 <0.0001
Advanced Stage
(III+IV) 70 87.22 70 90.89 70 88.7 70 94.7
Metastasis
M0 114 74 114 71.25 114 70.1 114 70.1
0.1 0.003 <0.0001 0.001
M1 40 87.49 40 95.31 40 98.59 40 98.59
Tumor Size (mm)
<70 77 69.42 77 71.22 77 68.92 77 67.73
0.024 0.08 0.017 0.007
>70 77 85.58 77 83.78 77 86.08 77 87.27
a

Number of patients

b

Groups were compared using Mann-Whitney U-test (Significant at P < 0.05)