Table 1. Clinicopathological features of SQCCs in never-smokers.
| Value | Frequency | Percentage |
|---|---|---|
| Gender | ||
| Male | 51 | 58.0% |
| Female | 37 | 42.0% |
| Age | ||
| < 55 | 21 | 23.9% |
| ≥ 55 | 67 | 76.1% |
| Mean (years) ± SD | 61.39 ± 10.40 | |
| Personal History of Malignant Tumor | ||
| Yes | 8 | 9.1% |
| No | 80 | 90.9% |
| Family History of Malignant Tumor | ||
| Yes | 9 | 10.2% |
| No | 79 | 89.8% |
| Locations of tumor | ||
| peripheral | 34 | 38.6% |
| central | 54 | 61.4% |
| N-stage | ||
| 0 | 45 | 51.1% |
| 1 | 16 | 18.2% |
| 2 | 26 | 29.5% |
| 3 | 1 | 1.1% |
| Differentiated Degree | ||
| well & moderate | 25 | 28.4% |
| poor | 62 | 70.5% |
| unknown & | 1 | 1.1% |
| Maximum length of tumor | ||
| < 3 | 15 | 17.0% |
| ≥ 3 | 70 | 79.6% |
| unavailable! | 3 | 3.4% |
| Mean (cm) ± SD | 4.43 ± 2.28 | |
| Methods of surgery | ||
| pneumonectomy | 9 | 10.2% |
| lobectomy* | 75 | 85.2% |
| others^ | 4 | 4.5% |
| Pathological stage | ||
| I | 34 | 38.6% |
| II | 20 | 22.7% |
| III | 31 | 35.2% |
| IV | 3 | 3.4% |
| oncogenic mutations | ||
| present’ | 16 | 18.2% |
| absent | 60 | 68.2% |
| unknown | 12 | 13.6% |
SD: standard deviation;
&
definite degree of differentiation was not determined for 1 patient.
!
could not be determined from the final pathological reports.
*
including 7 patients who received sleeve resection.
^
3 patients received wedge resection, 1 patient received sublobar resection.
§ including EGFR, KRAS, HER2, BRAF, AKT1, PIK3CA and FGFR.