Figure 2. HVJ-E inhibits MM cell growth in vivo in MM xenograft mouse models.

Tumor growth curves were measured in MM1S- (A) and NCI-H929-bearing (B) NOG mice. The tumor volume (mm³) (average and SEM) for each group of mice (n = 4–5/group) is shown. The mice were treated with PBS or 5,000 HAU of HVJ-E 3 times per week. A significant delay in tumor growth was noted in HVJ-E-treated mice in comparison to PBS-treated control mice (**P < 0.01, Student's unpaired t-test). The bars represent the mean ± SEM. Similar experiments were repeated twice, and the same results were obtained.