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. 2016 May 5;7(24):36207–36219. doi: 10.18632/oncotarget.9183

Figure 1. The levels of miR-200b and miR-200c are reduced in the steatotic livers of NAFLD patients and mice fed a HFD.

Figure 1

(A) Oil red O and H&E staining of the livers of HFD-fed mice. (B) The measurement of triglyceride levels in the livers of HFD-fed mice. (C) Western blots showing the expression of the lipogenic proteins SREBP1 and FAS. (D, F) Real-time reverse-transcription PCR showing the relative expression patterns of miR-200 family members including miR-200b, miR-200c, miR-200a, miR-141 and miR-429 in the steatotic livers of HFD-fed mice (n = 5) or in the livers of NAFLD patients and healthy subjects (n = 11). (E) H&E staining of the livers of NAFLD patients. (G) Western blots showing the expression of SREBP1 and FAS in the livers of NAFLD patients. The data represent the mean ± SEM. *P < 0.05 and **P < 0.01 versus the control. The bar represents 25 μm.