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. 2016 May 5;7(24):36207–36219. doi: 10.18632/oncotarget.9183

Figure 4. miR-200b and miR-200c bind to the 3′UTR of jun.

Figure 4

(A) TargetScan-predicted miR-200b and miR-200c bind to the 3′UTR of jun. (B) The luciferase reporter assay used to determine the effects of miR-200b and miR-200c on the relative luciferase activity of pmirGLO-jun-3′UTR. (C) Western blots showing the expression of the JUN protein in Hep1-6 cells transfected with miR-200b and miR-200c mimics. (D) Western blots showing the expression of the JUN protein in Hep1-6 cells transfected with miR-200b and miR-200c inhibitors. The data represent the mean ± SEM of three independent experiments. *P < 0.05 and **P < 0.01 versus the control.