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. 2016 Apr 18;7(24):36235–36246. doi: 10.18632/oncotarget.8827

Figure 6. Combinational regimen synergistically inhibited tumor growth of xenograft.

Figure 6

These nude mice were transplanted with SW13 cells, and assigned to four groups randomly after grown to appropriate volume, which were control (25mML(+)-tartaric acid p.o.), erlotinib (20mg/kg i.p.), NVP-AEW541 (20mg/kg p.o.) and combinational group (erlotinib and NVP-AEW541) for 21 days, each containing 8 mice. The tumor volumes were represented in Figure 6a. The comparison between NVP-AEW541 and control group, *: P<0.05; **: P<0.01. The comparison between erlotinib and control group, †: P<0.05; ††: P<0.01. The comparison between combinational and control group,#: P<0.05; ##: P<0.01. The gross appearances of tumors were represented in Figure 6b and body weights were represented in Figure 6c.