Table 1. Differentially expressed miRNAs of MYCN knockdown.
| miRNA | Stem-loop sequence | Average normalized read count of siMYCN | Average normalized read count of control | log2 fold-change (siMYCN/control) | Probability |
|---|---|---|---|---|---|
| miR-124-3p | mir-124-1 mir-124-2 mir-124-3 | 314.8 | 28.0 | 3.49 | 0.97 |
| miR-410-3p | mir-410 | 149.8 | 7.9 | 4.24 | 0.96 |
| miR-1307-3p | mir-1307 | 73.4 | 569.2 | −2.95 | 0.96 |
| miR-33a-5p | mir-33a | 42.3 | 4.7 | 3.18 | 0.93 |
| miR-1307-5p | mir-1307 | 18.5 | 2.1 | 3.16 | 0.90 |
| miR-27b-3p | mir-27b | 589.0 | 142.1 | 2.05 | 0.90 |
| miR-1268a | mir-1268a | 80.2 | 16.0 | 2.32 | 0.89 |
| miR-27a-3p | mir-27a | 68.2 | 14.5 | 2.23 | 0.88 |
| mir-873 | mir-873 | 66.4 | 14.1 | 2.23 | 0.88 |
| miR-92a-1-5p | mir-92a-1 | 108.4 | 377.0 | −1.80 | 0.87 |
| miR-331-3p | mir-331 | 32.4 | 7.1 | 2.19 | 0.85 |
| miR-1268b | mir-1268b | 89.8 | 25.6 | 1.81 | 0.85 |
| miR-130a-3p | mir-130a | 78.4 | 21.5 | 1.87 | 0.85 |
| miR-377-3p | mir-377 | 18.8 | 4.1 | 2.19 | 0.84 |
| miR-221-5p | mir-221 | 3.7 | 16.9 | −2.19 | 0.83 |
| miR-423-5p | mir-423 | 2111.4 | 5697.1 | −1.43 | 0.81 |
| miR-181d-5p | mir-181d | 167.7 | 505.2 | −1.59 | 0.81 |
| miR-345-5p | mir-345 | 10.6 | 2.7 | 1.96 | 0.81 |
| miR-887-3p | mir-887 | 3.6 | 12.2 | −1.77 | 0.80 |
| mir-92b | miR-92b-5p | 30.7 | 90.9 | −1.56 | 0.79 |
| miR-487b-3p | mir-487b | 249.7 | 96.9 | 1.37 | 0.78 |
| miR-181b-5p | mir-181b-1 mir-181b-2 | 862.6 | 2181.6 | −1.34 | 0.75 |
| miR-296-5p | mir-296 | 11.5 | 3.8 | 1.59 | 0.72 |
| miR-496 | mir-496 | 10.3 | 3.5 | 1.54 | 0.72 |
| miR-320a | mir-320a | 11660.9 | 24018.5 | −1.04 | 0.70 |
| miR-323a-3p | mir-323a | 1147.6 | 537.4 | 1.09 | 0.70 |
| miR-7-5p | mir-7-1 mir-7-2 mir-7-3 | 38.4 | 91.5 | −1.25 | 0.70 |
| miR-505-5p | mir-505 | 16.3 | 39.2 | −1.27 | 0.67 |
| miR-93-5p | mir-93 | 714.4 | 361.2 | 0.98 | 0.67 |
| miR-221-3p | mir-221 | 131.1 | 257.8 | −0.98 | 0.66 |
| miR-181a-5p | mir-181a-1 mir-181a-2 | 3045.0 | 5580.8 | −0.87 | 0.65 |
| miR-2110 | mir-2110 | 4.0 | 10.1 | −1.34 | 0.65 |
| miR-760 | mir-760 | 12.8 | 28.5 | −1.15 | 0.64 |
| miR-377-5p | mir-377 | 59.8 | 29.6 | 1.02 | 0.64 |
| miR-363-3p | mir-363 | 13.2 | 5.4 | 1.29 | 0.64 |
| miR-412-5p | mir-412 | 4.8 | 11.2 | −1.23 | 0.63 |
| miR-24-3p | mir-24-1 mir-24-2 | 959.0 | 547.1 | 0.81 | 0.63 |
| miR-330-3p | mir-330 | 58.2 | 106.3 | −0.87 | 0.62 |
| miR-1301-3p | mir-1301 | 106.8 | 185.2 | −0.79 | 0.62 |
| miR-382-5p | mir-382 | 266.3 | 157.3 | 0.76 | 0.61 |
| miR-222-3p | mir-222 | 578.5 | 959.9 | −0.73 | 0.61 |
| miR-323b-3p | mir-323b | 10.1 | 4.7 | 1.09 | 0.61 |
| miR-25-3p | mir-25 | 1434.6 | 875.3 | 0.71 | 0.61 |
| miR-376c-3p | mir-376c | 70.1 | 39.8 | 0.82 | 0.60 |
| miR-361-5p | mir-361 | 16.6 | 8.4 | 0.99 | 0.60 |
The list is sorted by “probability”. The probability derived from NOISeq indicates the “probability of differential expression”. The raw read counts were normalized by upper-quartile method.