Table 1. Characteristics of patients with CRC according to age-adjusted RTL of normal mucosa (nRTL).

A. Clinical Features	All	nRTL	P	P
		Mean±SD	(Uni.)	(Multi.)
Gender	n=419
Male	223	−0.13 ± 0.46
Female	196	0.02 ± 0.54	0.002*	0.002*
Site	n=419
Right	195	0.00 ± 0.51
Left	142	−0.11 ± 0.53	0.052	0.049*
Rectum	82	−0.10 ± 0.44	0.129	0.280
rs2736100	n=389
TT	111	−0.15 ± 0.43
TG	201	−0.08 ± 0.53
GG	77	0.13 ± 0.55	<0.001*	<0.001*
B. Lifestyle factors
BMI	n=229
Mean± SD	27.6 ± 5	-	0.522	0.417
Median	27.7
Range	15.2 to 43.1
Smoking	n=324
No	169	−0.08 ± 0.51
Yes	155	−0.12 ± 0.53	0.446	0.723

Abbreviations: A. Baseline clinical features and rs2736100 genotype, and B. lifestyle factors.

Uni. = univariate; Multi. = multivariate;

^*P<0.05.