Table 2. Biological parameters for early and late staged DN patients.
| Variables | Early Stage (n=37) | Late Stage (n=49) |
|---|---|---|
| Gender | ||
| Male | 18 | 23 |
| Female | 19 | 26 |
| Age (year) | 48.67±8.72 | 55.53±8.99# |
| History of DM (year) | 7.31±2.86 | 16.14±3.43# |
| SBP (mmHg) | 154.26±23.48 | 158.43±21.37 |
| DBP (mmHg) | 85.26±5.43 | 86.39±5.16 |
| Blood glucose (mmol/L) | 9.12±1.28 | 9.11±1.19 |
| Serum BUN (mmol/L) | 8.78±3.14 | 9.81±3.16* |
| Scr (umol/L) | 124.36±3.37 | 143.62±5.32# |
| Serum β2-microglobulin (mcg/mL) | 5.31±1.37 | 6.07±1.16* |
| Proteinuria (g/24h) | 0.46±0.28 | 5.18±2.26# |
| UACR (mg/mmol) | 186.75±11.13 | 315.42±16.34# |
| eGFR (ml/min.1.73m2) | 83.60±7.73 | 40.40±7.11# |
DM, diabetes mellitus; eGFR, estimated glomerular filtration rate; SBP, systolic blood pressure; DBP, diastolic blood pressure; Serum BUN, serum blood urea nitrogen; Scr, serum creatinine; UACR, urine albumin to creatinine ratio;
*
P<0.05
#
P<0.001.