Skip to main content
. 2016 May 6;7(24):36896–36908. doi: 10.18632/oncotarget.9213

Figure 4. The miR-507 inhibits VEGF-C expression through binding to the 3′UTR of human VEGF-C.

Figure 4

A. Schematic representation of the 3′UTR of the human VEGF-C containing a miR-507 binding site. B&C. Cells were cotransfected with miR-507 mimic or inhibitor and wt-VEGFC-3′UTR or mt-VEGFC-3′UTR plasmid for 24 h, and the relative luciferase/renilla activities were measured by luciferase reporter assay (n = 5). Results are expressed as the mean ± SE. *, p < 0.05 compared with JJ012 control; #, p < 0.05 compared with SW1353 control; †, p < 0.05 compared with CCL5-knockdowned group; ‡, p < 0.05 compared with CCL5-overexpressed group.